Best Weed Strains for Anxiety

A curated list of cannabis strains known for easing anxiety and stress. From high-CBD options like Cannatonic and ACDC to calming indicas like Granddaddy Purple — discover which anxiety-relief strains are currently in stock.

28 strains·20 in stock
1

Granddaddy Purple

Indica2 products

A go-to strain for anxiety relief, Granddaddy Purple delivers deep physical relaxation and a calming euphoria that melts away stress and racing thoughts.

2

Cannatonic

Hybrid

One of the most celebrated high-CBD strains, Cannatonic provides clear-headed relaxation without heavy sedation — ideal for daytime anxiety management.

3

Northern Lights

Indica3 products

A legendary indica known for its fast-acting, full-body calm. Northern Lights quiets anxious minds and eases tension with a dreamy, sedating effect.

4

Harlequin

Sativa

A rare CBD-dominant sativa that relieves anxiety without fogginess. Harlequin's balanced cannabinoid profile keeps you alert and relaxed simultaneously.

5

ACDC

Hybrid

With CBD-to-THC ratios as high as 20:1, ACDC is a powerhouse for anxiety relief with virtually no psychoactive effects — just pure calm.

6

Blue Dream

Hybrid26 products

A gentle, balanced hybrid that eases anxiety with uplifting cerebral effects and soothing body relaxation — a favorite for stress without sedation.

7

OG Kush

Hybrid6 products

Known for its stress-melting euphoria, OG Kush delivers a heavy wave of relaxation that can quiet even the most persistent anxiety.

8

Jack Herer

Sativa6 products

An energizing sativa that combats anxiety with clear-headed creativity and blissful focus — perfect for those who get anxious from sedating strains.

9

Girl Scout Cookies

Hybrid1 product

GSC delivers full-body relaxation paired with a euphoric mood lift that effectively combats stress, anxiety, and negative thought patterns.

10

Bubba Kush

Indica1 product

A heavy indica that wraps you in tranquilizing calm. Bubba Kush is prized for its ability to dissolve anxiety and promote deep physical ease.

11

Purple Kush

Indica

Pure indica bliss — Purple Kush delivers sedating, full-body relaxation that quiets anxious thoughts and promotes total peace of mind.

12

White Widow

Hybrid3 products

A burst of euphoria followed by steady relaxation, White Widow eases social anxiety and stress while keeping you conversational and present.

13

Strawberry Cough

Sativa21 products

Named for its sweet berry flavor, Strawberry Cough is a favorite for social anxiety — it uplifts mood and encourages easy, relaxed conversation.

14

Skywalker OG

Indica6 products

A potent indica-dominant hybrid that delivers heavy, calming effects perfect for unwinding after a stressful day and silencing anxious thoughts.

15

Zkittlez

Indica21 products

This award-winning strain provides a calming, focused high with a fruity flavor profile — ideal for anxiety relief without couch-lock.

16

Cherry Pie

Hybrid15 products

A balanced hybrid offering equal parts mental clarity and physical relaxation, Cherry Pie eases anxiety while keeping you functional and grounded.

17

Afghan Kush

Indica1 product

A pure landrace indica from the Hindu Kush mountains, Afghan Kush provides heavy sedation and deep calm that overwhelms anxiety and stress.

18

Blueberry

Indica65 products

Award-winning indica with sweet berry flavors and long-lasting euphoric relaxation that gently washes away stress and worry.

19

Sunset Sherbet

Hybrid

A dessert-flavored hybrid that eases stress with full-body relaxation and a dreamy, mood-elevating euphoria perfect for anxious evenings.

20

Ice Cream Cake

Indica9 products

Creamy, sweet, and deeply relaxing — Ice Cream Cake is a modern favorite for evening anxiety relief with its sedating body effects.

21

Forbidden Fruit

Indica5 products

A deeply relaxing indica with tropical fruit flavors that melts physical tension and promotes a tranquil, worry-free state of mind.

22

LA Confidential

Indica

A smooth, calming indica renowned for its ability to ease anxiety, stress, and insomnia with psychedelic relaxation and total body calm.

23

Runtz

Hybrid205 products

Balanced euphoria without overstimulation — Runtz delivers a calming, giggly high that lifts mood and eases anxious energy.

24

Purple Punch

Indica16 products

Like a one-two combo of Granddaddy Purple and Larry OG, Purple Punch sedates anxious minds with grape candy sweetness and heavy relaxation.

25

Headband

Hybrid5 products

Named for the gentle pressure sensation around the head, Headband provides long-lasting, smooth relaxation that keeps anxiety at bay for hours.

26

Master Kush

Indica

An Amsterdam classic that delivers grounded, earthy calm — Master Kush eases anxiety with a full-body relaxation that sharpens rather than dulls the senses.

27

Critical Mass

Indica

A high-CBD indica hybrid that provides mellow, pain-relieving relaxation and gentle calm — one of the best strains for anxiety sufferers seeking relief without intensity.

28

Gelato

Hybrid98 products

A dessert strain with balanced effects that ease anxiety through euphoric relaxation and a mellow body high without heavy sedation.

The Best Cannabis Strains for Anxiety Relief

These strains have earned a reputation for easing anxiety, stress, and racing thoughts. From high-CBD cultivars that deliver calm without intoxication to classic indicas that melt tension from head to toe, each strain on this list is chosen for its anxiolytic properties, proven track record, and availability as flower, pre-rolls, or edibles. Whether you prefer a clear-headed CBD strain for daytime use or a sedating indica for evening relief, these are the strains anxiety sufferers reach for most.

Best Weed Strains for Anxiety FAQs

Common questions about cannabis strains for anxiety relief

The best cannabis strains for anxiety include Granddaddy Purple, Cannatonic, Northern Lights, Harlequin, ACDC, Blue Dream, and OG Kush. High-CBD strains like Cannatonic and ACDC are especially effective because CBD can counteract the anxiety-inducing properties of THC while delivering calm, clear-headed relief.
Indica strains are generally considered better for anxiety because they promote physical relaxation and calm. However, some sativa strains like Harlequin and Jack Herer can also relieve anxiety through uplifting, clear-headed effects. The key factor is the strain's cannabinoid and terpene profile rather than the indica/sativa classification alone.
Yes, CBD-dominant strains like ACDC, Cannatonic, and Harlequin are among the most effective cannabis options for anxiety. CBD interacts with serotonin receptors and can reduce anxiety without the psychoactive effects of THC, making these strains ideal for daytime use and for those sensitive to THC.
Linalool (found in lavender), myrcene (found in mangoes and hops), and limonene (found in citrus) are terpenes commonly associated with anxiety relief. Strains rich in these terpenes, such as Granddaddy Purple (myrcene), Blueberry (linalool), and OG Kush (limonene), tend to deliver the most calming effects.
Yes, high-THC strains consumed in large doses can increase anxiety and paranoia in some people. To minimize this risk, start with low doses, choose strains with balanced THC-to-CBD ratios, and opt for strains known for calming effects. Our curated list focuses on strains with anxiety-relieving properties.
Strawberry Cough, White Widow, and Blue Dream are popular choices for social anxiety. They provide uplifting, euphoric effects that ease social tension while keeping you conversational and engaged. CBD-rich strains like Harlequin are also effective for social situations without causing intoxication.
Edibles can be effective for anxiety, especially low-dose options (2.5-5mg THC) or CBD-dominant edibles. They provide longer-lasting relief compared to smoking, but take 30-90 minutes to take effect. Start with a low dose and wait before consuming more, as edible effects can be more intense and longer-lasting.
Yes! King of Budz stocks many of the best strains for anxiety relief across our Michigan locations. Our Best Weed Strains for Anxiety collection shows you which calming strains are currently available as flower, pre-rolls, or edibles. Click on any product to see which store locations have it in stock.